Sitaformin 50/1000mg tablets combine two antidiabetic agents—Sitagliptin (50mg) and Metformin HCl (500mg)—to help manage type 2 diabetes more effectively, especially when diet and exercise alone aren’t enough.
Here’s how each component works:
- Metformin (a biguanide): Reduces glucose production in the liver, decreases intestinal absorption of glucose, and improves insulin sensitivity.
- Sitagliptin (a DPP-4 inhibitor): Enhances the body’s natural incretin hormones, which increase insulin release and reduce glucagon levels in response to meals.
Key uses:
- Controls blood sugar levels in type 2 diabetes.
- Helps reduce post-meal glucose spikes.
- May support weight management and cardiovascular health in diabetic patients.
Common side effects may include nausea, diarrhea, headache, or upper respiratory symptoms. Rarely, Metformin can cause lactic acidosis, a serious condition—so it’s important to use this medication under medical supervision.
If you’re curious about how this combo compares to other diabetes treatments or how it fits into a broader management plan, I’d be happy to walk you through it. Want to explore that?

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