Xanglu-Met 12.5/500mg tablets are a medication commonly prescribed for the management of type 2 diabetes mellitus. Here’s a summary:

– **Active Ingredients:** Xanglu-Met tablets contain two main ingredients:
– 12.5mg of a dipeptidyl peptidase-4 (DPP-4) inhibitor, which helps lower blood sugar levels by increasing the levels of incretin hormones in the body, thus stimulating the release of insulin and inhibiting the release of glucagon.
– 500mg of metformin hydrochloride, which is a biguanide-type medication that helps improve insulin sensitivity, decrease glucose production by the liver, and reduce glucose absorption in the intestines.

– **Dosage Form:** Tablets for oral administration.

– **Indications:** Xanglu-Met tablets are indicated for the management of type 2 diabetes mellitus, particularly in cases where diet and exercise alone have not been sufficient to control blood sugar levels. They help improve glycemic control by lowering fasting and postprandial blood glucose levels.

– **Administration:** Typically taken orally with water, usually with meals to reduce gastrointestinal side effects. Dosage and administration frequency are determined by a healthcare professional based on the patient’s individual needs and response to treatment.

– **Contraindications:** Xanglu-Met tablets are contraindicated in individuals with severe renal impairment, hepatic impairment, or metabolic acidosis. They should not be used in patients with type 1 diabetes or diabetic ketoacidosis.

– **Side Effects:** Common side effects may include gastrointestinal symptoms such as diarrhea, nausea, vomiting, abdominal discomfort, and loss of appetite. Rare but serious side effects may include lactic acidosis, pancreatitis, or allergic reactions.

– **Storage:** Store Xanglu-Met tablets at room temperature, away from light and moisture, and keep out of reach of children.

As with any medication, it’s crucial to use Xanglu-Met tablets as directed by a healthcare professional, following the prescribed dosage and frequency, and to monitor for any adverse effects or changes in blood sugar levels. Regular blood glucose monitoring and follow-up appointments with a healthcare provider are essential for effective management of diabetes.